No need to donate plasma, that might set off Frenzy…
Werewolf the Apocalypse was a bizarre fever dream of 90s influences. You had the whole enviro/new agey/appropriation of Native American stuff, which didn’t exactly fit in well with the cyberpunk stuff of the Glass Walkers and Bone Gnawers, the Shadow Lords and Silver Fangs being rather difficult to distinguish from Vampire clans, the shall we call them broad ethnic stereotypes of the Fianna or the Get of Fenris or the Silent Striders, etc.
Mostly, I would call Werewolf a bit too over-designed. Shape-shifting really should have been the central thing (although I think three forms rather than five would work better), but they added on Gnosis and the Umbra and spirits and spells and magic items on top of that. The three Breeds work (although the Metis stuff had problematic implications), but then they added on five Auspices and thirteen Tribes, and your character’s identity gets very complicated and blurry indeed.