I wouldn’t call them pretty loyal. They were one of the major contenders in the Dance, and they at least partially supported the Blackfyres during the Blackfyre Rebellion(s?).
House Hightower seems pretty loyal to House Targaryen despite Alicent Hightower and her line kind of getting jacked during the Dance of Dragons (to put it mildly). Pre-TWOIAF I thought maybe Maekar I’s wife could a Hightower since that could be a way to reconcile one of the most powerful houses in all Seven Kingdoms to the crown. Even with all the crown’s power, there are zillions of house with grudges for centuries-old stuff, why not only no grudge but high loyalty from the Hightowers?
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